Ghotki District Northern Sindh agricultural and industrial hub bordering Punjab — fertilizer, textiles, sugar, and energy, with five tehsils and headquarters at Mirpur Mathelo on the N-5 and Karachi–Peshawar railway. Read More
Khairpur District Largest district in the division by area — dates, wheat, cotton, rice, and sugarcane, with agro-processing, heritage sites, and Gambat medical facilities, headquarters at Khairpur City. Read More
Sukkur District Administrative and commercial hub of the division — trade, agriculture, industry, and services centered on Sukkur City, with Rohri, Pano Aqil, New Sukkur, and Saleh Pat, home to Sukkur Barrage and key N-5 / M-5 transport links. Read More
